ESXi 5.1 or 5.0, you mention 5.0 so the vSphere 5.0 SDK will be fine. If you have a 5.1 host, then you'll want to use the 5.1 SDK if you want to retrieve any new data properties exposed with the newer version. Also note, that 5.1 is backwards compat with prevous releases of vSphere which includes 5.0 & 4.x
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